Yes it can... But it works best when you 'pre-sell' a specific item with your content (an email or a blog post) and then link directly to that product's sales page on their site. Don't expect people to 'look around and shop' there... Give specific recommendations for the products that solve peoples' problems and link them directly to those products!
Developing and monetizing microsites can also garner a serious amount of sales. These sites are advertised within a partner site or on the sponsored listings of a search engine. They are distinct and separate from the organization’s main site. By offering more focused, relevant content to a specific audience, microsites lead to increased conversions due to their simple and straightforward call to action.
Affiliate marketing is commonly confused with referral marketing, as both forms of marketing use third parties to drive sales to the retailer. The two forms of marketing are differentiated, however, in how they drive sales, where affiliate marketing relies purely on financial motivations, while referral marketing relies more on trust and personal relationships.